Fe3O4
They are biocompatible, biodegradable, small enough to control and magnetically saturated, making them a popular choice in biomedicine. As a photothermal reagent, Fe3O4 has been recently in the spotlight.
Fe3O4 crystals that have the same structure are more photoconductive than Fe3O4 nucrystals. Fe3O4 microspheres, or Fe3O4-clusters, exhibit better photothermal effects due to Fe3O4’s stronger absorption functions in the far-infrared. Animal tests also showed that Fe3O4 photothermal treatments are more effective under near infrared light.
Further exploration of the photothermal characteristics of
Fe3O4
Researchers have investigated the photothermal properties of Fe3O4 nanospheres. The researchers found that microspheres larger than ligands are more absorbent in the nearinfrared and thus better at retaining light. Fe3O4 becomes partially oxidized when it is kept for longer periods of time. Researchers have found that Polymer Ligands (small molecule and polymer) have stronger protection against Fe3O4 Microspheres. They also have the stronger anti-oxidation abilities. Fe3O4 ball microspheres with stable polymer Ligands show a better photothermal effect as well as greater stability in photothermal conditions at the cell or animal level.
Fe3O4 nanoparticles can be used to enhance the photothermal properties of magnets. The core of Fe3O4&PDA composite microspheres has a shell structure. These microspheres have good biocompatibility and are made by the dopamine oxidatively self-polymerization. The composite microspheres are more absorbent in the near-infrared than Fe3O4 and have better photothermal properties. With increasing thickness of PDA shells, both the near-infrared absorption as well as photothermal effects of Fe3O4&PDA composite Microspheres increases.
When nanoparticles are introduced to the blood, they quickly combine with other proteins to create a protein crown. The protein crown is then swallowed, eliminated, or absorbed by the mononuclearphagocytes and reticuloendothelial and autoimmune systems. The biomimetic technique allows for the
Fe3O4
Red blood cell membranes (RBCs) are used to coat microspheres. They significantly increase long circulation of Fe3O4 microspheres throughout the body. The result is effective in encouraging the enrichment and subsequent improvement of animal levels.
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